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1

Biocompatibility of Tygon® tubing in microfluidic cell culture

Jiang, Xiao, Jeffries, Rex E., Acosta, Miguel A., Tikunov, Andrey P., Macdonald, Jeffrey M., Walker, Glenn M., Gamcsik, Michael P.

Journal:

Biomedical Microdevices

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

2

Synthesis of 15N and 17O labelled phosphoramide mustards

Susan M. Ludeman, Ellen M. Shulman-Roskes, Michael P. Gamcsik, Terence G. Hamill, Young H. Chang, Kyo I. Koo, O. Michael Colvin

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1993

Language:

english

File:

PDF, 564 KB

english, 1993

3

Improvements in solubility and stability of thalidomide upon complexation with hydroxypropyl-β-cyclodextrin

Martina Krenn, Michael P. Gamcsik, Georgia B. Vogelsang, O. Michael Colvin, Kam W. Leong

Journal:

Journal of Pharmaceutical Sciences

Year:

1992

Language:

english

File:

PDF, 490 KB

english, 1992

4

Glutathione levels in human tumors

Gamcsik, Michael P., Kasibhatla, Mohit S., Teeter, Stephanie D., Colvin, O. Michael

Journal:

Year:

2012

Language:

english

File:

PDF, 762 KB

english, 2012

5

ChemInform Abstract: Mechanisms of Resistance to the Toxicity of Cyclophosphamide

Michael P. Gamcsik, M. Eileen Dolan, Borje S. Andersson, David Murray

Journal:

Year:

1999

File:

PDF, 25 KB

1999

6

Synthesis of 13C-labeled derivatives of cysteine for magnetic resonance imaging studies of drug uptake and conversion to glutathione in rat brain

Prince N. A. Amoyaw, James B. Springer, Michael P. Gamcsik, Rebecca L. Mutesi, Michael A. D'Alessandro, Collin R. Dempsey, Susan M. Ludeman

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2011

Language:

english

File:

PDF, 175 KB

english, 2011

7

Synthesis of 15N labelled isophosphoramide mustard

Ellen M. Shulman-Roskes, Michael P. Gamcsik, O. Michael Colvin, Young H. Chang, Kyo I. Koo, Susan M. Ludeman

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1994

Language:

english

File:

PDF, 293 KB

english, 1994

8

Synthesis of 17O (and 18O) labelled isophosphoramide mustard

Sung Y. Han, Ellen M. Shulman-Roskes, Konrad Misiura, Lawrence W. Anderson, Edward Szymajda, Michael P. Gamcsik, Young H. Chang, Susan M. Ludeman

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1994

Language:

english

File:

PDF, 334 KB

english, 1994

9

In vivo MR studies of glycine and glutathione metabolism in a rat mammary tumor

Peter E. Thelwall, Nicholas E. Simpson, Zahid N. Rabbani, M. Daniel Clark, Roxana Pourdeyhimi, Jeffrey M. Macdonald, Stephen J. Blackband, Michael P. Gamcsik

Journal:

NMR in Biomedicine

Year:

2012

Language:

english

File:

PDF, 227 KB

english, 2012

10

13C-Isotopic Enrichment of Glutathione in Cell Extracts Determined by Nuclear Magnetic Resonance Spectroscopy

Michael P. Gamcsik

Journal:

Analytical Biochemistry

Year:

1999

Language:

english

File:

PDF, 83 KB

english, 1999

11

Determination of low levels of 4-fluorophenylalanine incorporation into proteins

Michael P. Gamcsik

Journal:

Analytical Biochemistry

Year:

1986

Language:

english

File:

PDF, 351 KB

english, 1986

12

Reduced blood flow increases the in vivo ammonium ion concentration in the RIF-1 tumor

Ioannis Constantinidis, Michael P. Gamcsik

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1995

Language:

english

File:

PDF, 768 KB

english, 1995

13

Intrastrand base-stacking buttresses widening of major groove in interstrand cross-linked B-DNA

Mateus Webba da Silva, Ross G. Bierbryer, Christopher J. Wilds, Anne M. Noronha, O. Michael Colvin, Paul S. Miller, Michael P. Gamcsik

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 908 KB

english, 2005

14

Role of glutathione and nucleotide excision repair in modulation of cisplatin activity withO6-benzylguanine

Melissa L. Fishel, Michael P. Gamcsik, Shannon M. Delaney, Eleanor G. Zuhowski, Veronica M. Maher, Theodore Karrison, Robert C. Moschel, Merrill J. Egorin, M. Eileen Dolan

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2005

Language:

english

File:

PDF, 399 KB

english, 2005

15

Camptothecin analogues with enhanced antitumor activity at acidic pH

David J. Adams, Mark W. Dewhirst, James L. Flowers, Michael P. Gamcsik, O. Michael Colvin, Govindarajan Manikumar, Mansukh C. Wani, Monroe E. Wall

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 176 KB

english, 2000

16

Evidence for a role of chloroethylaziridine in the cytotoxicity of cyclophosphamide

James L. Flowers, Susan M. Ludeman, Michael P. Gamcsik, O. Michael Colvin, Kai-Liu Shao, Jila H. Boal, James B. Springer, David J. Adams

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 321 KB

english, 2000

17

Non-invasive Monitoring of L-2-Oxothiazolidine-4-Carboxylate Metabolism in the Rat Brain by In vivo13C Magnetic Resonance Spectroscopy

Michael P. Gamcsik, M. Daniel Clark, Susan M. Ludeman, James B. Springer, Michael A. D’Alessandro, Nicholas E. Simpson, Roxana Pourdeyhimi, C. Bryce Johnson, Stephanie D. Teeter, Stephen J. Blackband,

Journal:

Neurochemical Research

Year:

2011

Language:

english

File:

PDF, 443 KB

english, 2011

18

Protonation of phosphoramide mustard and other phosphoramides

Gamcsik, Michael P., Ludeman, Susan M., Shulman-Roskes, Ellen M., McLennan, Ian J., Colvin, Michael E., Colvin, O. Michael

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 1.18 MB

english, 1993

19

NMR studies of the conjugation of mechlorethamine with glutathione

Gamcsik, Michael P., Hamill, Terence G., Colvin, Michael

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 751 KB

english, 1990

20

13C magnetic resonance spectroscopy detection of changes in serine isotopomers reflects changes in mitochondrial redox status

C. Bryce Johnson, Andrey P. Tikunov, Haakil Lee, Justyna E. Wolak, Peter Pediaditakis, Doug A. Romney, Ekhson Holmuhamedov, Michael P. Gamcsik, Jeffrey M. Macdonald

Journal:

Magnetic Resonance in Medicine

Year:

2012

Language:

english

File:

PDF, 486 KB

english, 2012

21

Fluorine nuclear magnetic resonance spectra of rabbit carbonmonoxyhemoglobin

Michael P. Gamcsik, J.T. Gerig, D.H. Gregory

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1987

Language:

english

File:

PDF, 993 KB

english, 1987

22

Noninvasive monitoring of glutathione turnover in perfused MCF-7 cells

Michael P. Gamcsik, Ross G. Bierbryer, Kevin K. Millis

Journal:

Free Radical Biology and Medicine

Year:

2004

Language:

english

File:

PDF, 231 KB

english, 2004

23

Increased rate of glutathione synthesis from cystine in drug-resistant MCF-7 cells

Michael P. Gamcsik, George R. Dubay, Brandon R. Cox

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 150 KB

english, 2002

24

Kinetics of the conjugation of aniline mustards with glutathione and thiosulfate

Michael P. Gamcsik, Kevin K. Millis, Terence G. Hamill

Journal:

Chemico-Biological Interactions

Year:

1997

Language:

english

File:

PDF, 392 KB

english, 1997

25

Role of glutathione in cellular resistance to alkylating agents

O.Michael Colvin, Henry S. Friedman, Michael P. Gamcsik, Catherine Fenselau, John Hilton

Journal:

Advances in Enzyme Regulation

Year:

1993

Language:

english

File:

PDF, 327 KB

english, 1993

26

Structure, Flexibility, and Repair of Two Different Orientations of the Same Alkyl Interstrand DNA Cross-Link †

Noll, David M., Webba da Silva, Mateus, Noronha, Anne M., Wilds, Christopher J., Colvin, O. Michael, Gamcsik, Michael P., Miller, Paul S.

Journal:

Year:

2005

Language:

english

File:

PDF, 656 KB

english, 2005

27

The Partitioning of Phosphoramide Mustard and Its Aziridinium Ions among Alkylation and P−N Bond Hydrolysis Reactions

Shulman-Roskes, Ellen M., Noe, Dennis A., Gamcsik, Michael P., Marlow, Allison L., Hilton, John, Hausheer, Frederick H., Colvin, O. Michael, Ludeman, Susan M.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 191 KB

english, 1998

28

Comparison of the Protonation of Isophosphoramide Mustard and Phosphoramide Mustard

Millis, Kevin K., Colvin, Michael E., Shulman-Roskes, Ellen M., Ludeman, Susan M., Colvin, O. Michael, Gamcsik, Michael P.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.26 MB

english, 1995

29

Accommodation of Mispair Aligned N 3 T-Ethyl-N 3 T DNA Interstrand Cross Link †

Webba da Silva, Mateus, Wilds, Christopher J., Noronha, Anne M., Colvin, O. Michael, Miller, Paul S., Gamcsik, Michael P.

Journal:

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

30

Solution Structure of a DNA Duplex Containing Mispair-Aligned N 4 C−Ethyl−N 4 C Interstrand Cross-Linked Cytosines †

Webba da Silva, Mateus, Noronha, Anne M., Noll, David M., Miller, Paul S., Colvin, O. Michael, Gamcsik, Michael P.

Journal:

Year:

2002

Language:

english

File:

PDF, 309 KB

english, 2002

31

Structure and stereochemistry of tetrahedral inhibitor complexes of papain by direct NMR observation

Gamcsik, Michael P., Malthouse, J. Paul G., Primrose, William U., Mackenzie, Neil E., Boyd, Alan S. F., Russell, Richard A., Scott, A. Ian

Journal:

Journal of the American Chemical Society

Year:

1983

Language:

english

File:

PDF, 266 KB

english, 1983

32

Cryoenzymology of proteases: NMR detection of a productive thioacyl derivative of papain at subzero temperatures

Malthouse, J. Paul G., Gamcsik, Michael P., Boyd, Alan S. F., Mackenzie, Neil E., Scott, A. Ian

Journal:

Journal of the American Chemical Society

Year:

1982

Language:

english

File:

PDF, 400 KB

english, 1982

33

Modified Guanines Representing O 6 -Alkylation by the Cyclophosphamide Metabolites Acrolein and Chloroacetaldehyde: Synthesis, Stability, and ab Initio Studies

Balu, Narayanan, Gamcsik, Michael P., Colvin, Michael E., Colvin, O. Michael, Dolan, M. Eileen, Ludeman, Susan M.

Journal:

Chemical Research in Toxicology

Year:

2002

Language:

english

File:

PDF, 97 KB

english, 2002

34

Noninvasive in vivo magnetic resonance measures of glutathione synthesis in human and rat liver as an oxidative stress biomarker

Skamarauskas, John T., Oakley, Fiona, Smith, Fiona E., Bawn, Carlo, Dunn, Michael, Vidler, Daniel S., Clemence, Matthew, Blain, Peter G., Taylor, Roy, Gamcsik, Michael P., Thelwall, Peter E.

Journal:

Year:

2014

Language:

english

File:

PDF, 781 KB

english, 2014

35

A microfluidic device to study cancer metastasis under chronic and intermittent hypoxia

Acosta, Miguel A., Jiang, Xiao, Huang, Pin-Kang, Cutler, Kyle B., Grant, Christine S., Walker, Glenn M., Gamcsik, Michael P.

Journal:

Biomicrofluidics

Year:

2014

Language:

english

File:

PDF, 2.35 MB

english, 2014

36

Two-Dimensional NMR Study of Bleomycin and Its Zinc(II) Complex: Reassignment of 13 C Resonances

Williamson, Daniel, McLennan, Ian J., Bax, Ad, Gamcsik, Michael P., Glickson, Jerry D.

Journal:

Journal of Biomolecular Structure and Dynamics

Year:

1990

Language:

english

File:

PDF, 1.18 MB

english, 1990

37

NMR Studies of the Interaction of Bleomycin with (dC-dG) 3

Gamcsik, Michael P., Glickson, Jerry D., Zon, Gerald

Journal:

Journal of Biomolecular Structure and Dynamics

Year:

1990

Language:

english

File:

PDF, 884 KB

english, 1990

38

Effect of Oxygen Concentration on Viability and Metabolism in a Fluidized-Bed Bioartificial Liver Using 31 P and 13 C NMR Spectroscopy

Jeffries, Rex E., Gamcsik, Michael P., Keshari, Kayvan R., Pediaditakis, Peter, Tikunov, Andrey P., Young, Gregory B., Lee, Haakil, Watkins, Paul B., Macdonald, Jeffrey M.

Journal:

Tissue Engineering Part C Methods

Year:

2013

Language:

english

File:

PDF, 447 KB

english, 2013

39

Computational analysis of structural and energetic consequences of DNA methylation

Hausheer, Frederick H., Rao, Shashidhar N., Gamcsik, Michael P., Kollman, Peter A., Colvin, O.Michael, Saxe, Jeffrey D., Nelkin, Barry D., McLennan, Ian J., Barnett, Gene, Baylin, Stephen B.

Journal:

Year:

1989

Language:

english

File:

PDF, 1.96 MB

english, 1989

40

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

Grahl, Nora, Puttikamonkul, Srisombat, Macdonald, Jeffrey M., Gamcsik, Michael P., Ngo, Lisa Y., Hohl, Tobias M., Cramer, Robert A., Filler, Scott G.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.09 MB

english, 2011

41

High-Throughput Nuclear Magnetic Resonance Metabolomic Footprinting for Tissue Engineering

Seagle, Christopher, Christie, Megan A., Winnike, Jason H., McClelland, Randall E., Ludlow, John W., O'Connell, Thomas M., Gamcsik, Michael P., MacDonald, Jeffrey M.

Journal:

Tissue Engineering Part C Methods

Year:

2008

Language:

english

File:

PDF, 653 KB

english, 2008

42

Mixing and delivery of multiple controlled oxygen environments to a single multiwell culture plate

Yao, Ming, Sattler, Tyler, Rabbani, Zahid N., Pulliam, Thomas, Walker, Glenn, Gamcsik, Michael P.

Journal:

American journal of physiology. Cell physiology

Year:

2018

Language:

english

File:

PDF, 8.20 MB

english, 2018

43

Flow-encoded oxygen control to track the time-dependence of molecular changes induced by static or cycling hypoxia.

Yao, Ming, Rabbani, Zahid N., Sattler, Tyler, Nguyen, Khue G., Zaharoff, David, Walker, Glenn, Gamcsik, Michael

Journal:

Analytical Chemistry

Year:

2019

Language:

english

File:

PDF, 973 KB

english, 2019